Ullrich, Heidrun and Mansouri-Taleghani, Behrouz and Lackner, Karl J. and Schalke, Berthold and Bogdahn, Ulrich and Schmitz, Gerd (1998) Chronic inflammatory demyelinating polyradiculoneuropathy: Superiority of protein A immunoadsorption over plasma exchange treatment. TRANSFUSION SCIENCE, 19. pp. 33-38. ISSN 0955-3886,
Full text not available from this repository. (Request a copy)Abstract
We present a patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) who was treated regularly with plasma exchanges (PE) because response to other therapies including i.v. immunoglobulins was not adequate. To reduce nonspecific protein losses due to repeated PE and increase IgG-removal, immunoadsorption (IA)therapy using sepharose-bound protein A was initiated. Retrospective analysis of clinical data including muscle strength and walking distance shows that IA led to more rapid and greater functional improvement than PE in this patient with no relevant side effects. After 3 years of therapy lymphoma was diagnosed and treated. The patient had no relapses of CIDP for 17 months, when his functional status deteriorated again necessitating further IA-therapy. It is concluded that IgG removal by IA in CIDP is more effective and has fewer complications than PE. Due to the chronic course of CIDP requiring repeated interventions IA is also not more expensive than PE. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GUILLAIN-BARRE-SYNDROME; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Sep 2023 13:21 |
| Last Modified: | 12 Sep 2023 13:21 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50072 |
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