Gap junctions in health and disease

Dermietzel, R. and Hofstaedter, Ferdinand (1998) Gap junctions in health and disease. VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY, 432 (2). pp. 177-186. ISSN 0945-6317,

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Abstract

An international symposium was held on gap junctions in health and disease in Regensburg, Germany, gathering together a panel of international scientists who discussed normal functions of gap junctions and their contribution to a variety of human diseases. The emphasis was on strategies and models for a better understanding of gap junction-mediated cell-to-cell communication in a variety of tissues, including null mutations of gap junction genes in recombinant transgenic mice. The topics varied from the normal function of cardiac gap junctions and its contribution to cardiac dysfunction up to the recently discovered point mutations of a gap junction gene encoding the gap junction protein connexin32 in Charcot-Marie-Tooth syndrome of the X1 type. A perspective of the future development of gap junction research and its contribution to unravelling pathophysiological mechanisms of human diseases was given by M.V.L. Bennett.

Item Type: Article
Uncontrolled Keywords: CELLS; COMMUNICATION; EXPRESSION; MODULATION; MUTATIONS; CHANNEL; INVIVO; GENE; gap junctions; genes; connexin; cell-to-cell communication
Subjects: 500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Pathologie
Biology, Preclinical Medicine > Institut für Anatomie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Oct 2023 08:03
Last Modified: 24 Oct 2023 08:03
URI: https://pred.uni-regensburg.de/id/eprint/50143

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