Wiesner, G. and Gruber, Michael and Hoerauf, K. and Taeger, Kai (1998) Protein binding of anaesthetics and adjuvant drugs. ANASTHESIOLOGIE & INTENSIVMEDIZIN, 39 (1). pp. 19-27. ISSN 0170-5334, 1439-0256
Full text not available from this repository.Abstract
Many anaesthetics are extensively bound to plasma proteins. This review article deals with the basic principles and the perioperative variability of protein binding. Furthermore the effects of perioperative alterations of protein binding on the pharmacokinetics and pharmacodynamics are elucidated. Many studies confirm the influence of protein binding on the uptake, (re)distribution, biotransformation and elimination of anaesthetics whereas the influence on drug effect is difficult to assess.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | protein binding; anaesthetics; pharmacokinetics; pharmacology |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 27 Jun 2024 10:59 |
| Last Modified: | 27 Jun 2024 10:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50164 |
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