Berti, M. and Candiani, G. and Kaufhold, A. and Muscholl, Albrecht and Wirth, Reinhard (1998) Does aggregation substance of Enterococcus faecalis contribute to development of endocarditis? INFECTION, 26 (1). pp. 52-57. ISSN 0300-8126,
Full text not available from this repository.Abstract
Aggregation substance (AS) of Enterococcus faecalis which is encoded by so-called sex pheromone plasmids enables the bacteria to bind to in vitro-cultured pig kidney tubular cells. It is reported that the presence of AS is not of pivotal importance for the ability of E. faecalis to cause infective endocarditis (EN). The lines of evidence far this are two-fold: 1) sex pheromone plasmids and, therefore, the gene for AS were not present more often in epidemiologically unrelated strains of E. faecalis isolated from human cases of EN than in isolates from well-water (26 vs. 18%); 2) the presence of the adhesin did not correlate with the establishment of EN in an animal (rat) model. The data are discussed with respect to the specificity of interaction of AS with eukaryotic cells and the results of other studies.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BACTERIAL SEX-PHEROMONE; STREPTOCOCCUS-FAECALIS; PLASMID TRANSFER; IDENTIFICATION; ADHESION; SYSTEM; CELLS; INDUCTION; INTEGRINS; VIRULENCE; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Mikrobiologie (Archaeenzentrum) > Prof. Dr. Reinhard Wirth |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Oct 2023 09:10 |
| Last Modified: | 31 Oct 2023 09:10 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50215 |
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