Zeuner, M. and Straub, Rainer H. and Schlosser, U. and Rauh, G. and Schmitz, G. and Schölmerich, Jürgen and Lang, B. (1998) Anti-phospholipid-antibodies in patients with relapsing polychondritis. LUPUS, 7 (1). pp. 12-14. ISSN 0961-2033,
Full text not available from this repository.Abstract
Relapsing polychondritis (RP) is an extremly rare multisystemic disease thought to be of autoimmune origin. in order to assess if RP is associated with anti-phospholipid antibodies (aPL), clinical data and sera of 21 patients with RP were collected in a multicentre study. Concentration of anti-cardiolipin antibodies (aCL) (IgG-, IgM- and IgA-isotypes), anti-phosphatidylserine-antibodies (aPS) (IgG- and IgM-isotypes) and anti-beta-2-glycoprotein I-antibodies (a beta 2 GPI) were measured by ELISA. In eight patients aCL were found to be elevated. One patient had elevated aPS. No patient had elevated a beta 2 GPI. No patient had clinical signs and symptoms of a aPL syndrome. Interestingly, the two RP patients with the highest aPL had concomitant systemic lupus erythematosus (SLE). Therefore the presence of elevated aPL in RP is probably more closely related to an associated SLE than to RP itself. There is no convincing evidence that aPL are associated with RP.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ANTIPHOSPHOLIPID ANTIBODIES; LUPUS ANTICOAGULANT; anti-phospholipid antibodies; relapsing polychondritis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 31 Oct 2023 10:11 |
| Last Modified: | 31 Oct 2023 10:11 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50256 |
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