Strotzer, M and Gmeinwieser, J and Schmidt, J and Fellner, C and Seitz, J and Albrich, H and Zirngibl, H and Feuerbach, S (1997) Diagnosis of liver metastases from colorectal adenocarcinoma - Comparison of spiral-CTAP combined with intravenous contrast-enhanced spiral-CT and SPIO-enhanced MR combined with plain MR imaging. ACTA RADIOLOGICA, 38 (6). pp. 986-992. ISSN 0284-1851,
Full text not available from this repository.Abstract
Purpose: The purpose of this study was to determine whether MR with and without SPIO (AMI-25) could replace spiral-CTAP in the staging of colorectal adenocarcinoma. Material and Methods: Thirty-five patients were studied prospectively by means of i.v. contrast-enhanced spiral-CT, spiral-CTAP, and MR of the liver. MR imaging was performed before and after infusion of AMI-25. Diagnoses were compared to intraoperative findings (n=35) which included intraoperative ultrasound (n=21), and follow-up CT (n=18). Results and Conclusion; Fifteen patients were found to have a total number of 53 liver metastases and 43 benign lesions were detected. Evaluation was performed in four different ways: 1) i.v. contrast-enhanced spiral-CT; 2) i.v. contrast-enhanced spiral-CT + spiral-CTAP; 3) plain MR; 4) plain MR + SPIO-enhanced MR. I.v. contrast-enhanced spiral-CT, spiral-CTAP and SPIO-enhanced MR identified patients with liver metastases with equal sensitivity. However, owing to its significantly higher sensitivity, based on a lesion-by-lesion analysis, spiral-CTAP cannot be replaced by SPIO-enhanced MR in patients who are to undergo liver resection. A limitation in spiral-CTAP is its relatively low specificity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SUPERPARAMAGNETIC IRON-OXIDE; FOCAL HEPATIC-LESIONS; ARTERIAL PORTOGRAPHY; INTRAOPERATIVE US; DELAYED CT; CANCER; RESECTION; EFFICACY; FERUMOXIDES; SAFETY; liver neoplasms, diagnosis; CT, helical technology; portography; iron; MR |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:30 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50416 |
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