Ito, K and Sass, H and Urban, J and Hofbauer, A and Schneuwly, S (1997) GAL4-responsive UAS-tau as a tool for studying the anatomy and development of the Drosophila central nervous system. CELL AND TISSUE RESEARCH, 290 (1). pp. 1-10. ISSN 0302-766X,
Full text not available from this repository.Abstract
To improve the quality of cytoplasmic labelling of GAL4-expressing cells in Drosophila enhancer-trap and transgenic strains, a new GAL4-responsive reporter UAS-tau, which features a bovine tau cDNA under control of a yeast upstream activation sequence (UAS), was tested. Tau, a microtubule-associated protein, is distributed actively and evenly into all cellular processes. Monoclonal anti-bovine Tau antibody reveals the axonal structure of the labelled cells with detail similar to that of Golgi impregnation. We demonstrate that the UAS-tau system is especially useful for studying processes of differentiation and reorganisation of identified neurones during postembryonic development.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEURONAL ARCHITECTURE; BETA-GALACTOSIDASE; GENE-EXPRESSION; FUSION PROTEIN; GLIAL-CELLS; OPTIC LOBE; MELANOGASTER; METAMORPHOSIS; GANGLION; INSECT; brain; postembryonic development; metamorphosis; neurone; enhancer trap; Drosophila melanogaster (Insecta) |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:31 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50499 |
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