Karrer, S and Abels, C and Baumler, W and Steinbauer, M and Landthaler, M and Szeimies, RM (1997) Photochemotherapy with indocyanine green of cutaneous metastases of rectal carcinoma. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 122 (37). pp. 1111-1114. ISSN 0012-0472, 1439-4413
Full text not available from this repository.Abstract
History and admission findings: Six weeks before admission of a 47-year-old man with known rectal carcinoma, small nodular metastases had occurred over the front of both his thighs. Examination showed many aggregate cuti-color or livid nodes, diameter 0,5 cm. The patient's poor general condition excluded the usual palliative measures. Treatment and course: Photochemotherapy of the skin metastases with indocyanine green (ICG; absorption maximum 805 nm), a non-toxic dye approved for diagnostic purposes, was undertaken on a trial basis. The dye, being bound to plasma proteins, is retained in the intravacular space. Immediately after administration of the dye (2.5 mg/kg intravenously) the skin metastases were irradiated by diode laser (lambda=805 nm, 100J/cm(2), 3 W/cm(2), radiation diameter 2 cm). This necrosed the metastases and clinically as well as histologically resulted in their complete disappearance with scarring of the treated area. Conclusion: This case illustrates the effectiveness of photochemotherapy with ICC against solid skin tumours of increased microvascular density.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:31 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50558 |
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