Gleich, O and Strutz, J (1997) Age-dependent effects of the onset of a conductive hearing loss on the volume of the cochlear nucleus subdivisions and the expression of c-fos in the mongolian gerbil (Meriones unguiculatus). AUDIOLOGY AND NEURO-OTOLOGY, 2 (3). pp. 113-127. ISSN 1420-3030,
Full text not available from this repository.Abstract
A monaural conductive hearing loss was induced by interrupting the chain of the middle ear ossicles on the right side in gerbils of four different age groups (P12-14, P20-21, P42 and P84). The volumes of the cochlear nucleus subdivisions and the number of cells that expressed immunoreactivity for c-fos after noise stimulation were determined on the left and right side in the deprived animals, and in undeprived control animals when they reached the age of 6 months. The anteroventral cochlear nucleus on the deprived side was reduced in volume when the deprivation started before the age of 3 months. The other cochlear nucleus subdivisions showed no systematic age-dependent reductions. The expression of c-fos in the dorsal cochlear nucleus appeared more resistant to a hearing loss, with deprivation being more effective in younger animals. c-fos expression was also dramatically reduced in the ventral cochlear nucleus, regardless of age at the onset of hearing loss.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | AUDITORY BRAIN-STEM; NERVE ELECTRICAL-ACTIVITY; INFERIOR COLLICULUS; ACOUSTIC DEPRIVATION; OTITIS-MEDIA; AFFERENT INFLUENCES; CELL-SIZE; RAT; REMOVAL; PROJECTIONS; development; maturation; deprivation; deafness; cochlear nucleus morphology |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/50837 |
Actions (login required)
 |
View Item |
