Kröger, Nils and Bergsdorf, Christian and Sumper, Manfred (1996) Frustulins: Domain conservation in a protein family associated with diatom cell walls. EUROPEAN JOURNAL OF BIOCHEMISTRY, 239 (2). pp. 259-264. ISSN 0014-2956
Full text not available from this repository.Abstract
The outstanding feature of a diatom is the species-specific design and ornamentation of the silica-based cell wall, termed frustulum. A new frustulum is shaped in a specialized organelle (silica deposition vesicle) and secreted. Proteins in the lumen of this organelle may control the biomineralization process and are likely to remain associated with the mature cell wall. Therefore a study of the structures of proteins associated with the diatom cell wall was initiated. The complete primary structures of three cell wall proteins (denoted as frustulins) have been determined. In addition, partial amino acid sequences from two more cell wall components were obtained. From these data, a highly conserved domain has been identified as a common building block of diatom cell wall proteins that is repeated several times per polypeptide chain together with polyproline/hydroxyproline or polyglycine spacers. All frustulins characterized so far, are synthesized as preproteins with a novel type of N-terminal presequence.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DNA; diatom; cell wall; hydroxyproline-rich glycoprotein; presequence; Cylindrotheca fusiformis |
| Subjects: | 500 Science > 540 Chemistry & allied sciences 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Alumni or Retired > Prof. Dr. Manfred Sumper |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Jul 2023 05:07 |
| Last Modified: | 05 Jul 2023 05:07 |
| URI: | https://pred.uni-regensburg.de/id/eprint/51599 |
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