The Saccharomyces cerevisiae kinetochore

Lechner, Johannes and Ortiz, Jennifer (1996) The Saccharomyces cerevisiae kinetochore. FEBS LETTERS, 389 (1). pp. 70-74. ISSN 0014-5793, 1873-3468

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Abstract

Accurate chromosome segregation is dependent on a specialized chromosomal structure, the kinetochore/centromere. The only essential constituent of the S, cerevisiae kinetochore established today is CBF3, a multisubunit complex that binds to S, cerevisiae centromere DNA. Therefore CBF3 and its four components, Cbf3a, Cbf3b, Cbt3c and Cbf3d, will form the centerpiece of this review. In addition, we will describe proteins that are putatively involved in kinetochore function specifically in the context with CBF3 interaction, Furthermore, we discuss the role of the S. cerevisiae kinetochores in a putative cell cycle checkpoint control and in microtubule attachment.

Item Type: Article
Uncontrolled Keywords: CENTROMERE DNA; BUDDING YEAST; CHROMOSOME SEGREGATION; PROTEIN COMPLEX; BINDING; MICROTUBULES; COMPONENT; INVITRO; centromere; kinetochore; CBF3; Saccharomyces cerevisiae
Subjects: 500 Science > 570 Life sciences
Divisions: Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 05 Jul 2023 06:21
Last Modified: 05 Jul 2023 06:21
URI: https://pred.uni-regensburg.de/id/eprint/51635

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