Terfort, Andreas and Brunner, Henri (1996) Phosphane ligands with two binding sites of differing hardness for enantioselective Grignard cross coupling. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (12). pp. 1467-1479. ISSN 0300-922X
Full text not available from this repository.Abstract
A series of new, chiral phosphanes is presented, individual members of which were designed to serve as ligands in transition-metal mediated asymmetric Grignard cross coupling reactions. These ligands are characterized by a side chain containing one or two oxygen atoms with the capacity to act as binding sites for the incoming Grignard reagent, A number of structural parameters for the compounds was varied to learn about the reaction mechanism, Most of the ligands were tested in two cross coupling reactions, the formation of 3-phenylbut-1-ene and of 2,2'-dimethyl-1,1'-binaphthyl, respectively, Although both systems gave modest enantiomeric excesses it was not possible to make a comparison of their respective abilities.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CATALYTIC ASYMMETRIC DIHYDROXYLATION; TRANSITION-METAL-COMPLEXES; SUBSTITUTED OLEFINS; PHOSPHORUS LIGANDS; NICKEL-COMPLEXES; AUXILIARIES; IMPROVEMENT; DERIVATIVES; PHOSPHINES; MECHANISM |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Anorganische Chemie > Alumni or Retired Professors > Prof. Dr. Henri Brunner |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Jul 2023 06:30 |
| Last Modified: | 05 Jul 2023 06:30 |
| URI: | https://pred.uni-regensburg.de/id/eprint/51638 |
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