Intraoperative autotransfusion with blood irradiation in cancer surgery: Principles and application

Hansen, E and Taeger, K (1996) Intraoperative autotransfusion with blood irradiation in cancer surgery: Principles and application. ANASTHESIOLOGIE & INTENSIVMEDIZIN, 37 (6). pp. 306-312. ISSN 0170-5334,

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Abstract

The frequent identification of tumour cells in the blood shed during tumour surgery in high numbers, showing vitality, invasiveness and tumourigenicity, confirmed the contraindication of any direct retransfusion of that blood. The cell saver itself, or leucocyte depletion filters are not able to eliminate these cells completely. Instead, blood irradiation with 50Gy provides a sufficient, high efficiency of tumour cell elimination which was confirmed experimentally. Blood irradiation for intraoperative blood salvage in cancer surgery representing the combination of two established procedures also is safe, and has proven its practicability in clinical practice. It makes available a powerful method for reducing homologous blood transfusions in cancer patients.

Item Type: Article
Uncontrolled Keywords: TUMOR-CELLS; AUTO-TRANSFUSION; AUTOLOGOUS TRANSFUSION; COLORECTAL-CANCER; HOST DISEASE; CARCINOMA; SEPARATION; METASTASES; RESECTION; surgery, operative; neoplasms; blood transfusion, autologous; radiation
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:35
URI: https://pred.uni-regensburg.de/id/eprint/51654

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