Gallbladder motility in systemic sclerosis

Lock, G and Zeuner, M and Kammerl, M and Lang, B and Scholmerich, J and Holstege, A (1996) Gallbladder motility in systemic sclerosis. RHEUMATOLOGY INTERNATIONAL, 16 (2). pp. 61-65. ISSN 0172-8172,

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Abstract

In 20 patients with systemic sclerosis (SSc) and 24 healthy controls, gallbladder motility was evaluated by abdominal ultrasonography after stimulation by a standard liquid meal, Results from patients with normal and disturbed oesophageal function were analysed separately in order to investigate the significance of gallbladder motility as a parameter for gastrointestinal involvement in SSc. All patients showed a marked decrease in gallbladder size after stimulation (patients 61 +/- 13%; controls 48 +/- 12%). Patients with oesophageal dysfunction (n = 12) had a slightly lower gallbladder contraction (maximal decrease = 58 +/- 13%) when compared to patients with normal oesophageal function (n = 8; 66 +/- 13%); however, this difference was not statistically significant. Gallbladder motility in patients with SSc was not reduced when compared with healthy controls. SSc-induced oesophageal dysfunction was not associated with impaired gallbladder motility. Thus, measurement of gallbladder emptying is not a helpful tool when looking for gastrointestinal involvement in SSc.

Item Type: Article
Uncontrolled Keywords: GASTROINTESTINAL MANIFESTATIONS; ESOPHAGEAL DYSFUNCTION; SCLERODERMA PATIENTS; PATHOGENESIS; ERYTHROMYCIN; gallbladder motility; systemic sclerosis; ultrasonography; oesophageal manometry
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:35
URI: https://pred.uni-regensburg.de/id/eprint/51692

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