Synthesis of carbazole derivatives .3. Synthesis of new pyrrolidino[3,4-c]carbazoles by intramolecular Michael addition

Mahboobi, Sioavosh and Kuhr, Sabine and Koller, Markus (1996) Synthesis of carbazole derivatives .3. Synthesis of new pyrrolidino[3,4-c]carbazoles by intramolecular Michael addition. TETRAHEDRON, 52 (18). pp. 6373-6382. ISSN 0040-4020

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Abstract

We have reported on the synthesis of carbazoles by inter- and intramolecular Michael addition. Ellipticine derivatives are related to these compounds, and especially those with 9-methoxy- and 9-hydroxy substituents exhibit appreciable antitumor and antileukemic activity. Therefore, we have prepared the tetrahydrocarbazoles 7a and 7b, starting from N-benzyl-2-formyl-5-methoxyindole (2a) and N-benzyl-2-formyl-7-methoxyindole (2b), respectively. Copyright (C) 1996 Published by Elsevier Science Ltd

Item Type: Article
Uncontrolled Keywords: INDOLES; syntheses of carbazoles and pyrrolidones by intramolecular Michael addition
Subjects: 500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Divisions: Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Jul 2023 09:45
Last Modified: 06 Jul 2023 09:45
URI: https://pred.uni-regensburg.de/id/eprint/51766

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