Initial acro-osteolysis ulcero-mutilans in two brothers with hereditary type I motor sensory neuropathy

Karrer, S and Szeimies, RM and Landthaler, M (1996) Initial acro-osteolysis ulcero-mutilans in two brothers with hereditary type I motor sensory neuropathy. EUROPEAN JOURNAL OF DERMATOLOGY, 6 (1). pp. 11-13. ISSN 1167-1122,

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Abstract

Two brothers aged 43 and 39, presented with indolent ulcerations with hyperkeratotic margins at the lateral sole of the feet. Both patients complained of pes cavus-like deformation. There was no history of diabetes mellitus or alcohol abuse. Neurologic examinations revealed glove-stocking impairment of all sensory modalities, paresis and atrophy of the intrinsic musculature of the feet and lower legs. Motor nerve conduction velocity measurements were markedly slowed. Roentgenologic findings consisted of osteolysis in the bones of the feet in regions of increased pressure. Clinical findings, history and neurological examinations confirmed the diagnosis of familial acro-osteolysis ulcero-mutilans (Thevenard syndrome) based on an hereditary type I motor sensory neuropathy.

Item Type: Article
Uncontrolled Keywords: ; acro-osteolysis ulcero-mutilans; Thevenard syndrome; hereditary type I motor sensory neuropathy
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:36
URI: https://pred.uni-regensburg.de/id/eprint/52031

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