Kriegmair, M and Baumgartner, R and Knuchel, R and Stepp, H and Hofstadter, F and Hostetter, A (1996) Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. JOURNAL OF UROLOGY, 155 (1). pp. 105-109. ISSN 0022-5347, 1527-3792
Full text not available from this repository.Abstract
Purpose: We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence. Materials and Methods: A 3% 5-aminolevulinic acid solution was instilled intravesically before cystoscopy in 104 patients. The 5-aminolevulinic acid induced porphyrin fluorescence was excited by violet light from a krypton ion laser (wavelength 406.7 nm.). Results: The sensitivity of the fluorescence cystoscopy (96.9%) was significantly (p < 0.0001) greater than that of white light cystoscopy (72.7%). There was no impact on specificity, Conclusions: Due to the high sensitivity of the procedure fluorescence guided biopsies are recommended instead of random biopsies,
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CARCINOMA; DIAGNOSIS; BIOPSIES; TUMORS; MUCOSA; bladder neoplasms; aminolevulinic acid; fluorescence; protoporphyrins |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/52089 |
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