Treatment of severe localized scleroderma by plasmapheresis report of three cases

Wach, F. and Ullrich, H. and Schmitz, G. and Landthaler, Michael and Hein, R. (1995) Treatment of severe localized scleroderma by plasmapheresis report of three cases. BRITISH JOURNAL OF DERMATOLOGY, 133 (4). pp. 605-609. ISSN 0007-0963, 1365-2133

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Abstract

We report three patients with severe, localized scleroderma, and with elevated titres of antinuclear antibodies, who were treated by plasmapheresis in combination with systemic steroid therapy. The therapeutic effectiveness of plasmapheresis was assessed on the basis of improvement in cutaneous and joint lesions, In all cases, significant improvement occurred after 2 months of therapy. Thus, in addition to treating systemic sclerosis, plasmapheresis can also be recommended for treatment of severe cases of localized scleroderma with elevated titres of antinuclear antibodies and antibodies to ss-DNA.

Item Type: Article
Uncontrolled Keywords: PROGRESSIVE SYSTEMIC-SCLEROSIS; SINGLE-STRANDED-DNA; IMMUNOSUPPRESSIVE DRUG-THERAPY; PLASMA-EXCHANGE; LINEAR SCLERODERMA; CUTANEOUS SCLERODERMA; INTERFERON-ALPHA; ANTIBODIES; MORPHEA; SKIN
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Depositing User: Petra Gürster
Date Deposited: 19 Dec 2024 13:20
Last Modified: 19 Dec 2024 13:20
URI: https://pred.uni-regensburg.de/id/eprint/52280

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