Langguth, Berthold and Sturm, Kornelia and Wetter, Thomas C. and Lange, Max and Gabriels, Loes and Mayer, Emeran A. and Schlaier, Juergen (2015) Deep Brain Stimulation for Obsessive Compulsive Disorder Reduces Symptoms of Irritable Bowel Syndrome in a Single Patient. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 13 (7). 1371-+. ISSN 1542-3565, 1542-7714
Full text not available from this repository. (Request a copy)Abstract
Irritable bowel syndrome (IBS) is a frequent gastrointestinal disorder that is difficult to treat. We describe findings from evaluation of a woman (55 years old) with obsessive compulsive disorder, which was treated with bilateral deep brain stimulation in the anterior limb of the internal capsule, and IBS. After the brain stimulation treatment she reported substantial relief of her IBS symptoms. This reduction depended on specific stimulation parameters, was reproducible over time, and was not directly associated with improvements in obsessive compulsive disorder symptoms. These observations indicate a specific effect of deep brain stimulation on IBS. This observation confirms involvement of specific brain structures in the pathophysiology of IBS and shows that symptoms can be reduced through modulation of neuronal activity in the central nervous system. Further studies of the effects of brain stimulation on IBS are required.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | IBS; Deep Brain Stimulation; Irritable Bowel Syndrome; Brain Gut Axis; Neuroplasticity |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurochirurgie Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Jul 2019 07:24 |
| Last Modified: | 08 Jul 2019 07:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/5230 |
Actions (login required)
 |
View Item |
