STEUER, MK and HOFSTADTER, F and PROBSTER, L and BEUTH, J and STRUTZ, J (1995) ARE ABH ANTIGENIC DETERMINANTS ON HUMAN OUTER EAR CANAL EPITHELIUM RESPONSIBLE FOR PSEUDOMONAS-AERUGINOSA INFECTIONS. ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 57 (3). pp. 148-152. ISSN 0301-1569,
Full text not available from this repository.Abstract
The outer ear canal expression of ABH human blood group antigens has been analyzed with a standardized routine histological procedure by monoclonal antibodies in the case of blood groups A and B, and a corresponding lectin in the case of blood group 0, respectively. In all 20 cases the blood groups were histochemically confirmed. Furthermore, Pseudomonas aeruginosa-specific inhibition experiments were performed with different sugar solutions as well as A-like substance incubating outer ear canal tissue sections with P. aeruginosa strain (No. 60) presenting lectin specificity for N-acetyl-galactosamine (GalNAc). P. aeruginosa lectins with GalNAc specificity apparently adhere to GalNAc as terminal blood group A determinant and indicate that patients presenting with blood group A may have a genetic predisposition to this form of otitis externa.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; ABH ANTIGENIC DETERMINANTS; HUMAN OUTER EAR CANAL; PSEUDOMONAS AERUGINOSA LECTINS; ABO BLOOD GROUP |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:37 |
| URI: | https://pred.uni-regensburg.de/id/eprint/52574 |
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