THE EFFECTS OF ABLATION DIAMETER ON THE OUTCOME EXCIMER-LASER PHOTOREFRACTIVE KERATECTOMY - A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND-STUDY

OBRART, DPS and CORBETT, MC and LOHMANN, CP and MUIR, MGK and MARSHALL, J (1995) THE EFFECTS OF ABLATION DIAMETER ON THE OUTCOME EXCIMER-LASER PHOTOREFRACTIVE KERATECTOMY - A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND-STUDY. ARCHIVES OF OPHTHALMOLOGY, 113 (4). pp. 438-443. ISSN 0003-9950,

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Abstract

Objective: To determine the effects of the ablation diameter on the outcome of excimer laser photorefractive keratectomy. Design: Eighty patients were randomized to either a 5.00-mm or a 6.00-mm treatment group and within these groups underwent either a -3.00-diopter (D) or a -6.00-D correction based on their preoperative refraction. A Summit Omnimed excimer laser was used throughout the study. Results: In eyes treated with a 6.00-mm-diameter ablation, the initial hyperopic shift was reduced, with significant differences at 1 week with -3.00-D corrections and at 1 and 4 weeks with -6.00-D corrections (P<.01). At 6 months, the refractive changes were greater and closer to that intended with 6.00-mm-diameter ablations. The predictability of photorefractive keratectomy was significantly improved with 6.00-mm zones, with a reduction in variance of the refractive changes at all stages postoperatively (P<.05 to P<.001). With -3.00-D corrections, objective measurements showed significantly less anterior stromal haze in eyes treated with 6.00-mm zones at 6 months (P<.05). With -6.00-D corrections, haze was significantly reduced at 1, 3, and 6 months in the eyes treated with 6.00-mm zones (P<.05). Five eyes treated with 5.00-mm zones experienced severe regression of the correction, with marked corneal haze and a reduction of 3 or more lines of best corrected Snellen visual acuity at 6 months. No eyes treated with 6.00-mm zones were similarly affected. Computerized measurements of ''night'' halo were significantly lower in the 6.00-mm treatment groups at 1 week and at 1 and 6 months in the eyes with -3.00-D corrections and at 1 week and at 1 month in the eyes with -6.00-D corrections (P<.05). At 6 months, seven patients treated with 5.OO-mm zones complained of severe disturbances of night night vision. No eyes in the 6.00-mm group were similarly affected. Conclusions: Treatment with 6.00-mm ablation diameters precipitated less initial overcorrection, greatly improved the predictability of photorefractive keratectomy, and was associated with a reduction in complications impairing postoperative visual performance.

Item Type: Article
Uncontrolled Keywords: FOLLOW-UP; SURGERY;
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:37
URI: https://pred.uni-regensburg.de/id/eprint/52612

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