SANZ, JL and HUBER, G and HUBER, H and AMILS, R (1994) USING PROTEIN-SYNTHESIS INHIBITORS TO ESTABLISH THE PHYLOGENETIC-RELATIONSHIPS OF THE SULFOLOBALES ORDER. JOURNAL OF MOLECULAR EVOLUTION, 39 (5). pp. 528-532. ISSN 0022-2844,
Full text not available from this repository.Abstract
The sensitivity of the cell-free protein synthesis systems from Acidanus brierleyi, Acidianus infernus, and Metallosphaera sedula, members of the archaeal order Sulfolobales, to 40 antibiotics with different specificities has been studied. The sensitivity patterns were compared to those of Sulfolobus solfataricus and other archaeal, bacterial, and eukaryotic systems. The comparative analysis shows that ribosomes from the sulfolobales are the most refractory to inhibitors of protein synthesis described so far. The sensitivity results have been used to ascertain in phylogenetic relationships among the members of the order Sulfolobales. The evolutionary significance of these results are analyzed in the context of the phylogenetic position of this group of extreme thermophilic microorganisms.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RIBOSOMAL-RNA; GEN-NOV; ARCHAEBACTERIA; SENSITIVITY; SYSTEM; SULFOLOBALES; PROTEIN SYNTHESIS; ANTIBIOTICS; RIBOSOMAL FUNCTION |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/53004 |
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