STOLZ, W and RIEMANN, A and COGNETTA, AB and PILLET, L and ABMAYR, W and HOLZEL, D and BILEK, P and NACHBAR, F and LANDTHALER, M and BRAUNFALCO, O (1994) ABCD RULE OF DERMATOSCOPY - A NEW PRACTICAL METHOD FOR EARLY RECOGNITION OF MALIGNANT-MELANOMA. EUROPEAN JOURNAL OF DERMATOLOGY, 4 (7). pp. 521-527. ISSN 1167-1122,
Full text not available from this repository.Abstract
To improve and facilitate differentiation between benign melanocytic naevi (MN) and malignant melanoma (MM), a new ABCD rule has been developed on the basis of semiquantitative analysis of 31 features of surface microscopy at 10x (dermatoscopy) on micrographs of 62 histologically proven MN and 95 early MM (tumor thickness < 1 mm), which were randomly divided into a training and a test set. Multivariate analysis revealed that by combining the scores of four features (range in parentheses) (Asymmetry )(0-2), Border (0-8), Colour (1-6), and Differential structure (1-5) (ABCD)) in a formula (A x 1.3 + B x 0.1 + Cx 0.5 + D x 0.5 = Final dermatoscopy Score (FDS)), a diagnostic accuracy of 94%, specificity of 90.3%, and sensitivity of 100.0% could be achieved in the training set. With this ABCD rule of dermatoscopy, which can be easily learned and quickly calculated, a lesion is considered malignant, if the FDS exceeds 5.45. Reliability of the new ABCD rule was proven by a diagnostic accuracy of 92.2% and 97.9%, and specificity of 90.3% in the test set.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PIGMENTED SKIN-LESIONS; INVIVO EPILUMINESCENCE MICROSCOPY; SURFACE MICROSCOPY; CLINICAL-DIAGNOSIS; ACCURACY; ABCD RULE OF DERMATOSCOPY; QUANTITATIVE SKIN SURFACE MICROSCOPY; MELANOCYTIC LESIONS |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/53050 |
Actions (login required)
 |
View Item |
