INDUCTION OF STRESS FIBERS AND INTERCELLULAR GAPS IN HUMAN VASCULAR ENDOTHELIUM BY SHOCK-WAVES

SEIDL, M and STEINBACH, P and WORLE, K and HOFSTADTER, F (1994) INDUCTION OF STRESS FIBERS AND INTERCELLULAR GAPS IN HUMAN VASCULAR ENDOTHELIUM BY SHOCK-WAVES. ULTRASONICS, 32 (5). pp. 397-400. ISSN 0041-624X,

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Abstract

Human umbilical cords were exposed to high amplitude focussed ultrasonic pulses with focal energy densities 0.6 and 0.4 mJ mm-2. The endothelium of the exposed vessel (vein) was examined by means of confocal laser scanning microscopy and scanning electron microscopy. The degree of tissue change ranged from the induction of stress fibres and intercellular gaps to the complete detachment of endothelial cells combined with damage of the basement membrane. An increased number of stress fibres may indicate an increased vessel wall permeability. This might explain the enhanced effects in experimental tumour therapy that have been found by other authors when combining shock-waves with drugs.

Item Type: Article
Uncontrolled Keywords: BIOLOGICAL RESPONSE MODIFIERS; LITHOTRIPSY; FIBERS; SHOCK-WAVES; ENDOTHELIAL CELLS; STRESS FIBERS; INTERCELLULAR GAPS; FOCUSED ULTRASOUND
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:40
URI: https://pred.uni-regensburg.de/id/eprint/53128

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