1,3-DINITROPROPANES - INTERMEDIATES TO 1,3-DIAMINOPROPANES

MAHBOOBI, S and GROTHUS, G (1994) 1,3-DINITROPROPANES - INTERMEDIATES TO 1,3-DIAMINOPROPANES. ARCHIV DER PHARMAZIE, 327 (6). pp. 349-358. ISSN 0365-6233,

Full text not available from this repository.

Abstract

Reduction of malodininiles 4 and 10 to the corresponding diamines does not work. - Reduction of dinitro-2-(indol-3-yl)-propanes 13 and 16 and subsequent reaction with K2PtCl4 afford the corresponding dichloroplatinum(II) complexes 14 and 17. Complexes 17 show weak binding affinities to the estrogen receptor and no antitumor activity towards MCF-7- and MDA-MB-2231-cell lines. - Twofold addition of nitromethane to aldehyde 24 is possible.

Item Type: Article
Uncontrolled Keywords: ESTROGEN-RECEPTOR AFFINITY; TUMOR INHIBITING ACTIVITY; 2-PHENYLINDOLES; ANTAGONISTS;
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:40
URI: https://pred.uni-regensburg.de/id/eprint/53244

Actions (login required)

View Item View Item