STENGL, M (1994) INOSITOL-TRISPHOSPHATE-DEPENDENT CALCIUM CURRENTS PRECEDE CATION CURRENTS IN INSECT OLFACTORY RECEPTOR NEURONS IN-VITRO. JOURNAL OF COMPARATIVE PHYSIOLOGY A-SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 174 (2). pp. 187-194. ISSN 0340-7594,
Full text not available from this repository.Abstract
Specialized olfactory receptor neurons in insects respond to species-specific sex pheromones with transient rises in inositol trisphosphate and by opening pheromone-dependent cation channels. These channels resemble cation channels which are directly or indirectly Ca2+-dependent. But there appear to be no internal Ca2+ stores in the outer dendrite where the olfactory transduction cascade is thought to start. Hence, it remains to be determined whether an influx of external Ca2+ precedes pheromone-dependent cation currents. Patch clamp measurements in cultured olfactory receptor neurons from Manduca sexta reveal that a transient inward current precedes pheromone-dependent cation currents. A transient inositol trisphosphate-dependent Ca2+ current, also preceding cation currents with the characteristics of pheromone-dependent cation currents, shares properties with the transient pheromone-dependent current. These results match the biochemical measurements with the electrophysiological data obtained in insect olfactory receptor neurons.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MOTH MANDUCA-SEXTA; SENSITIVE ADENYLATE-CYCLASE; CYCLIC-GMP; ANTHERAEA-POLYPHEMUS; PHEROMONE BLEND; CELLS; ANTENNAE; CONDUCTANCE; ACTIVATION; CHANNEL; INSECT CELL CULTURE; MANDUCA SEXTA; OLFACTORY TRANSDUCTION; 2ND MESSENGERS; SEX PHEROMONE |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/53481 |
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