WROBEL, KH and KUJAT, R and LUTZ, R (1993) EXPRESSION OF THE PROLIFERATION-ASSOCIATED KI-67 ANTIGEN IN BOVINE TESTICULAR TUBULAR CELLS DURING THE SEMINIFEROUS EPITHELIAL CYCLE, DEMONSTRATED WITH THE MIB-1 ANTIBODY. ANDROLOGIA, 25 (5). pp. 301-305. ISSN 0303-4569,
Full text not available from this repository.Abstract
Ki-67 expression in the seminiferous tubule of the bovine testis was studied by immunohistochemistry during the seminiferous epithelial cycle using the monoclonal antibody MIB-1. Spermatogonial proliferation is most obvious in stages 5-7, and 8, when B-spermatogonia divide. A lower rate of spermatogonial propagation is observed preceding or during meiosis in stages 1-4. The MIB-1 antibody also gives positive results with some post-spermatogonial tubular cells. Preleptotenes passing through S-phase in stage 1 reveal positive nuclei. During prophase of meiosis I pachytenes react strongly, diplotenes react in an attenuated manner, while leptotenes and zygotenes stay negative. Secondary spermatocytes seen in stage 4 are positive as are the chromosomes during meta- and anaphase of the meiotic divisions. Post-meiotic spermatids are also decorated but stop Ki-67 expression abruptly at the end of stage 4. Sertoli cells are negative.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LOCALIZATION; SPERMATOGENESIS; PEROXIDASE; DETECTS; TESTIS; SPERMATOGENESIS; KI-67 ANTIGEN; MIB-1 ANTIBODY; BOVINE |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:42 |
| URI: | https://pred.uni-regensburg.de/id/eprint/53778 |
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