MANNSCHRECK, A (1993) ONLINE MEASUREMENT OF CIRCULAR-DICHROISM SPECTRA DURING ENANTIOSELECTIVE LIQUID-CHROMATOGRAPHY. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 12 (5). pp. 220-225. ISSN 0165-9936,
Full text not available from this repository.Abstract
Liquid chromatography on enantioselective sorbents offers the possibility of exploiting circular dichroism (CD) to obtain spectra on-line, i.e. without preparative enrichment of the species of interest. The simplest 'stop-flow' procedure requires the chromatographic flow to be stopped at the peak maximum for the optically active material of interest; during this period, a CD spectrum is obtained under normal scanning conditions. In the more complex mode, CD spectra are acquired by 'non-stop' rapid-scanning of sequential spectra by means of a multiwavelength CD detector. In this over-view, the future of chiroptical detection in separation science is discussed with reference to the wide variety of chiral molecules of current interest in the fields of chemistry, pharmacy and biology.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHIROPTICAL DETECTION; ENANTIOMERS; HPLC; |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:42 |
| URI: | https://pred.uni-regensburg.de/id/eprint/53993 |
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