IWASA, K and KAMIGAUCHI, M and SAIKI, K and TAKAO, N and WIEGREBE, W (1993) O-METHYLATING ENZYMES OF DOPAMINE AND DOPAMINE DERIVED TETRAHYDROISOQUINOLINE, SALSOLINOL. PHYTOCHEMISTRY, 32 (6). pp. 1443-1448. ISSN 0031-9422,
Full text not available from this repository.Abstract
By using an LC/API-MS system, it was demonstrated that dopamine condenses with acetaldehyde to give salsolinol which is further metabolized to produce 6-O-methylsalsolinol (isosalsoline) which is O- and N-methylated to provide salsolidine and N-methylisosalsoline, respectively, in several plant tissue cultures of Papaveraceae. Almost none of the 3-O-methoxytyramine formed from dopamine was metabolized into simple isoquinoline derivatives. Although salsolinol and 3-O-methoxytyramine were formed from dopamine, no O-methylatedsalsolinol was formed in tissue cultures of Cynanchum vincetoxicum (Asclepiadaceae). The results suggest that the 0-methylating enzymes Of salsolinol may be different to those of dopamine.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TISSUE-CULTURES; BRAIN; CORYDALIS-PALLIDA VAR TENUIS, C-OCHOTENSIS VAR RADDEANA, C-INCISA; MACLEAYA-CORDATA; PAPAVERACEAE; CYNANCHUM-VINCETOXICUM; ASCLEPIADACEAE; DOPAMINE; ISOQUINOLINE ALKALOIDS; TISSUE CULTURES; METABOLISM |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:42 |
| URI: | https://pred.uni-regensburg.de/id/eprint/54044 |
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