ENANTIOSELECTIVE CATALYSIS .83. SYNTHESIS OF OPTICALLY-ACTIVE FERROCENYLALANINE

BRUNNER, H and KONIG, W and NUBER, B (1993) ENANTIOSELECTIVE CATALYSIS .83. SYNTHESIS OF OPTICALLY-ACTIVE FERROCENYLALANINE. TETRAHEDRON-ASYMMETRY, 4 (4). pp. 699-707. ISSN 0957-4166,

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Abstract

Ferrocenylalanine, a possible substitute for phenylalanine in the commercial sweetener aspartame, was synthesized by asymmetric hydrogenation of the corresponding dehydro acylamino acids with rhodium/phosphine catalysts in up to 94% enantiomeric excess. The absolute configuration of N-benzoyl-ferrocenyl alanine 4 was determined by single-crystal X-ray analysis.

Item Type: Article
Uncontrolled Keywords: HYDROGENATION; COMPLEXES; PEPTIDES; NORPHOS; ACID;
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:42
URI: https://pred.uni-regensburg.de/id/eprint/54045

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