Laser treatment or intravitreal VEGF inhibition for aggressive posterior retinopathy of prematurity?

Barth, T. and Hufendiek, K. and Helbig, H. and Oberacher-Velten, I. (2015) Laser treatment or intravitreal VEGF inhibition for aggressive posterior retinopathy of prematurity? OPHTHALMOLOGE, 112 (6). pp. 520-524. ISSN 0941-293X, 1433-0423

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Abstract

A prematurely born male infant (24+5 gestational weeks, birth weight 485 g) was diagnosed with bilateral aggressive posterior retinopathy of prematurity (AP-ROP) in zone I. After obtaining informed written consent from the parents, one eye was treated with diode laser photocoagulation and the other eye with 0.25 mg intravitreal ranibizumab. Laser photocoagulation was found to be an effective tool for fast regression of AP-ROP; however, medium-term evaluation showed poor macular formation and peripheral retinal detachment. The intravitreal injection led to a slower but better control of the AP-ROP and central foveal reflexes showed better anatomical outcome.

Item Type: Article
Uncontrolled Keywords: ; Diode laser photocoagulation; Ranibizumab; Avascular retinal areas; Retinal detachment; Vascular endothelial growth factor
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Jul 2019 06:28
Last Modified: 15 Jul 2019 06:28
URI: https://pred.uni-regensburg.de/id/eprint/5408

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