GLIENKE, W and VONBRIESEN, H and ESSER, R and MULLER, S and ANDREESEN, R and RUBSAMENWAIGMANN, H (1993) EXPRESSION OF MACROPHAGE PRODUCTS AFTER INVITRO INFECTION OF HUMAN MONOCYTES MACROPHAGES WITH HIV. RESEARCH IN VIROLOGY, 144 (1). pp. 35-40. ISSN 0923-2516,
Full text not available from this repository.Abstract
We studied the response of monocytes/macrophages (MO/MAC) to lipopolysaccharide (LPS) and interferon-gamma (IFNgamma) stimulation with respect to the expression of macrophage-specific products, i.e. macrophage-colony-stimulating factor (M-CSF), c-fms, c-sis, tissue factors, transforming growth factor-beta (TGFbeta) and interleukin-8 (IL8) after in vitro infection with HIV. The expression of IL8 was strongly elevated in HIV-infected cells, peaking at 4 h after stimulation with LPS. At that time, the uninfected control showed only weak expression of IL8. Other products, e.g. tissue factor, c-fms, M-CSF and TGFbeta were not modulated after stimulation. In contrast to IL8, the expression of c-sis was significantly lower in infected cells after stimulation with IFNgamma compared to uninfected control cells.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSFORMING GROWTH-FACTOR; AIDS PATIENTS; TISSUE; RECEPTOR; VIRUS; BETA; HIV, MONOCYTE, MACROPHAGE, CYTOKINE; IFN, LPS, EXPRESSION, IL8, MESSENGER RNA |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/54216 |
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