BIOLOGICAL AND BIOSYNTHETIC-PROPERTIES OF POLY-L-MALATE

HOLLER, E and ANGERER, B and ACHHAMMER, G and MILLER, S and WINDISCH, C (1992) BIOLOGICAL AND BIOSYNTHETIC-PROPERTIES OF POLY-L-MALATE. FEMS MICROBIOLOGY LETTERS, 103 (2-4). pp. 109-118. ISSN 0378-1097,

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Abstract

Beta-poly-L-malate (PMA) is a highly soluble polyanion specifically synthesized during the plasmodial stage of the life cycle in Physarum polycephalum. The polymer partitions in a growth-dependent fashion between cell nuclei, the cytoplasm and the culture medium, where it is slowly hydrolyzed. It strongly interacts with certain soluble nuclear proteins suggesting the function as a mobile matrix involved in stock-piling of such molecules and required in the synchronization of the nuclear cell division typical for plasmodia. It is synthesized continuously over the cell cycle during growth involving a PMA polymerase that seems genetically related to the enzyme catalyzing in certain bacteria the polymerization of poly-beta-hydroxybutyrate.

Item Type: Article
Uncontrolled Keywords: PHYSARUM-POLYCEPHALUM; DNA-POLYMERASE; ACID); POLYESTER; BIODEGRADABLE POLYMER; POLYANION; POLY-L-MALATE; SYNCYTIC CELLS; PHYSARUM-POLYCEPHALUM; PLASMODIUM
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:44
URI: https://pred.uni-regensburg.de/id/eprint/54264

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