STEREOISOMERIC [1,2-BIS(3-HYDROXYPHENYL)ETHYLENEDIAMINE]PLATINUM(II) COMPLEXES .3. EVALUATION OF THE MAMMARY-TUMOR INHIBITING PROPERTIES

SCHERTL, S and GUST, R and MULLER, R and SPRUSS, T and SCHONENBERGER, H (1992) STEREOISOMERIC [1,2-BIS(3-HYDROXYPHENYL)ETHYLENEDIAMINE]PLATINUM(II) COMPLEXES .3. EVALUATION OF THE MAMMARY-TUMOR INHIBITING PROPERTIES. ARCHIV DER PHARMAZIE, 325 (2). pp. 113-118. ISSN 0365-6233,

Full text not available from this repository.

Abstract

Stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]platinum(II) complexes produce a strong configuration-dependent inhibition of the hormone sensitive MXT-mammary carcinoma of the mouse. Besides an interference in the DNA synthesis in analogy to cisplatin an estrogen level lowering effect is supposed to be the mode of action. The new complexes show also a significant activity on the hormone-independent MXT-mammary carcinoma of the mouse.

Item Type:	Article
Uncontrolled Keywords:	BREAST-CANCER; HETEROGENEITY;
Depositing User:	Dr. Gernot Deinzer
Last Modified:	19 Oct 2022 08:44
URI:	https://pred.uni-regensburg.de/id/eprint/54650

Actions (login required)

View Item