CHEMICAL-STRUCTURE AND BIOLOGICAL-ACTIVITY OF POLYSACCHARIDES FROM HIBISCUS-SABDARIFFA

MULLER, BM and FRANZ, G (1992) CHEMICAL-STRUCTURE AND BIOLOGICAL-ACTIVITY OF POLYSACCHARIDES FROM HIBISCUS-SABDARIFFA. PLANTA MEDICA, 58 (1). pp. 60-67. ISSN 0032-0943,

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Abstract

Three water-soluble polysaccharides have been isolated from flower buds of Hibiscus sabdariffa L. (HIB 1, 2, 3). The neutral polysaccharides (HIB 1 and 2) are composed of arabinans and arabinogalactans of low relative molecular mass. The major fraction was investigated by methylation analysis, pectinase-treatment, mild acid hydrolysis, and NMR studies, and it was shown to be a pectin-like molecule (M(r) = 10(5) d). The main chain is composed of alpha-1,4-linked GalA (24% methyl-esterified) and alpha-1,2-linked Rha. Side chains are built of Gal and Ara and are connected to the main chain via C-4 of every third Rha. Its structure seems to be different from polysaccharide structures described in other species of the Hibiscus genus and the Malvaceae family. All fractions were assayed for possible immune-modulating effects. All fractions showed some activity, but the main acidic fraction was contaminated with lipopolysaccharide, and therefore its shown activity has to be discussed carefully.

Item Type: Article
Uncontrolled Keywords: PLANT MUCILAGES; REPRESENTATIVE MUCILAGE; SYRIACUS; LEAVES; HIBISCUS-SABDARIFFA; MALVACEAE; POLYSACCHARIDES; PECTIN; IMMUNOLOGICAL ACTIVITY
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:44
URI: https://pred.uni-regensburg.de/id/eprint/54670

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