SCHOBER, C and SCHMOLL, E and SCHMOLL, HJ and POLIWODA, H and SCHUPPERT, F and STAHL, M and BOKEMEYER, C and WILKE, H and WEISS, J (1992) ANTITUMOR EFFECT AND SYMPTOMATIC CONTROL WITH INTERFERON-ALPHA-2B IN PATIENTS WITH ENDOCRINE ACTIVE-TUMORS. EUROPEAN JOURNAL OF CANCER, 28A (10). pp. 1664-1666. ISSN 0959-8049,
Full text not available from this repository.Abstract
26 patients with progressive neuroendocrine tumours received 3 x 10(6)U/m2 interferon alfa (IFN-alpha-2b) subcutaneously thrice weekly, until progression, as outpatients with moderate toxicity. 4/16 carcinoids and none out of 10 endocrine pancreatic tumours showed objective regression. Another 17 patients (68%) had no change. For a median of 34 weeks symptom control was excellent: 9 of 17 patients had major relief from pain, 11 of 13 from diarrhoea, and 7 of 7 from flushing. Thus, low-dose INF-alpha-2b, given thrice weekly might be as effective as daily treatment with higher dosages. Treatment was only administered to patients with progression or major symptoms and this did not seem to adversely affect remission quality and survival.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TUMORS; ALPHA; |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/54695 |
Actions (login required)
 |
View Item |
