BRUNNER, H and KURZWART, M (1992) ASYMMETRIC CATALYSIS .73. ENANTIOSELECTIVE DECARBOXYLATION OF METHYLPHENYLMALONIC ACID-DERIVATIVES WITH CU(I) ALKALOID CATALYSTS. MONATSHEFTE FUR CHEMIE, 123 (1-2). pp. 121-128. ISSN 0026-9247,
Full text not available from this repository.Abstract
Methylphenylmalonic acid was decarboxylated to yield 2-phenylpropionic acid with an optical induction of 36% ee using catalytic amounts of CuCl and an excess of (+)-cinchonine in acetonitril. Methylphenylmalonic acid hemiethylester gave ethyl 2-phenylpropionate of 20% ee with catalytic amounts of CuCl and (+)-cinchonine, respectively. The tetraethylammonium salt of methylphenylmalonic acid could be decarboxylated in the presence of CuCl, (+)-cinchonine, and chiral carboxylic acids, the best result of 27% ee being obtained with malic acid.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | QUINOLINE; KINETICS; DECARBOXYLATION; ENANTIOSELECTIVITY; MALONIC ACID DERIVATIVES; ALKALOIDS, CU CATALYSIS |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/54723 |
Actions (login required)
 |
View Item |
