PRAGER, G and PRAGER, R and KLEIN, P and KONIG, S (1992) COMPARISON OF CIRCADIAN BLOOD-PRESSURE PROFILE IN ELDERLY SUBJECTS WITH ISOLATED SYSTOLIC HYPERTENSION, ESSENTIAL-HYPERTENSION, AND NORMOTENSION. ZEITSCHRIFT FUR KARDIOLOGIE, 81. pp. 63-65. ISSN 0300-5860,
Full text not available from this repository.Abstract
In order to evaluate circadian blood-pressure (BP) profile characteristics typical of old age, we compared circadian BP profile in elderly subjects with isolated systolic hypertension (ISH; > 160/ < 90 mmHg), essential hypertension (EH; diastolic BP greater-than-or-equal-to 95 mmHg), and normotension (N; < 140/ < 90 mmHg). Each group consisted of 18 subjects, approximately matched in age and sex, (age range 60-82 years; mean age 67.5 years). Ambulatory 24-h BP-monitoring was carried out using a SpaceLabs 90202 with measurements made every 30 min. In ISH, casual systolic BP is higher and circadian systolic BP is lower than in EH (n.s.). Circadian diastolic BP is lower than in EH and higher than in N; both are statistically highly significant (p < 0.001, u-test, Wilcoxon). The decrease during the resting period is 6 mmHg in EH and 17 mmHg in ISH. in ISH there is a considerable difference of 39 mmHg between casual BP and circadian 24-h BP, in contrast to N and to EH, and this is due to a particular hyperreactivity. This discrepancy is typical of old age and holds the danger of over-treatment, if only casual BP is taken into consideration.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MORTALITY; AMBULATORY BLOOD PRESSURE MONITORING; ELDERLY; SYSTOLIC HYPERTENSION; ESSENTIAL HYPERTENSION; NORMOTENSION; OVER-TREATMENT |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/54745 |
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