SCHILLER, CD and VONANGERER, E and SCHNEIDER, MR (1991) 6,7-DIHYDRO-4H-INDOLONES - SYNTHESIS AND BIOLOGICAL PROPERTIES. ARCHIV DER PHARMAZIE, 324 (10). pp. 767-771. ISSN 0365-6233,
Full text not available from this repository.Abstract
Syntheses of 6,7-dihydro-4H-indolones 6 and 10 by a selective Birch reduction of the benzene ring of the indole system are described. The antiestrogen zindoxifene and the 2-phenylindole 2 as well as 6 and 10 were tested for their relative binding affinities at the androgen receptor as well as for antiandrogenic and estrogenic properties. Both compounds 6 and 10 showed potent indirect antiandrogenic activity which were similar to those of the 2-phenylindoles zindoxifene and 2.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TUMOR-INHIBITING ACTIVITY; ESTROGENS; RAT; |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:46 |
| URI: | https://pred.uni-regensburg.de/id/eprint/54826 |
Actions (login required)
 |
View Item |
