SIDE-EFFECTS OF THE TOPICAL APPLICATION OF VASOCONSTRICTORS .1. CATECHOLAMINES

HANSEN, E and KEYL, C and LEMBERGER, P (1991) SIDE-EFFECTS OF THE TOPICAL APPLICATION OF VASOCONSTRICTORS .1. CATECHOLAMINES. ANASTHESIOLOGIE & INTENSIVMEDIZIN, 32 (7). pp. 191-196. ISSN 0170-5334,

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Abstract

The local application of catecholamines as the vasoconstrictor element of local anaesthetics, or to achieve bloodlessness in the area of the wound may be expected to give rise to systemic side effect when, as a result of rapid absorption from well-perfused tissue, or unintentional intravascular injection, there is a rise in the plasma catecholamine levels. This may be the case even at low dosages. A hazard to the patient will present in particular when, as a result of prior disease or the use of medication, enhanced sensitivity to catecholamines is present. For application during general anaesthesia, the use of halothane should be avoided. Characteristic adverse reactions are an increase in the heart rate and systolic blood pressure, an elevation of the myocardial oxygen consumption, and the triggering of arrhythmias. Patients with coronary heart disease are at a particular risk. The application of noradrenalin (norepinephrine) as a vasoconstrictor ist not recommended.

Item Type: Article
Uncontrolled Keywords: ;
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:46
URI: https://pred.uni-regensburg.de/id/eprint/54953

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