1,2-DIPHENYL-1-PYRIDYL-BUT-1-ENES-POTENTIAL ANTIESTROGENS .2. BIOLOGICAL EVALUATION

SCHWARZ, W and HARTMANN, RW and SCHONENBERGER, H (1991) 1,2-DIPHENYL-1-PYRIDYL-BUT-1-ENES-POTENTIAL ANTIESTROGENS .2. BIOLOGICAL EVALUATION. ARCHIV DER PHARMAZIE, 324 (4). pp. 231-234. ISSN 0365-6233,

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Abstract

Z-1-(4-hydroxyphenyl)-1-(4-resp. 3-pyridyl)-2-phenyl-but-1-enes Z-1 and Z-2 and their acetates Z-1a and Z-2a are weak estrogens (uterine weight test, immature mouse), which cause a marked tumor growth inhibition on the hormone-dependent MXT mammary carcinoma of the mouse. No or just slight estrogenic side effects determined by uterine weight are detectable in this tumor experiment.

Item Type: Article
Uncontrolled Keywords: ACETOXY-SUBSTITUTED 1,1,2-TRIPHENYLBUT-1-ENES; TUMOR INHIBITING ACTIVITY; MAMMARY-TUMOR; TAMOXIFEN; MCF-7;
Depositing User: Dr. Gernot Deinzer
Last Modified: 19 Oct 2022 08:46
URI: https://pred.uni-regensburg.de/id/eprint/55030

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