GLADIALI, S and PINNA, L and DELOGU, G and GRAF, E and BRUNNER, H (1990) OPTICALLY-ACTIVE PHENANTHROLINES IN ASYMMETRIC CATALYSIS .4. ENANTIOSELECTIVE HYDROSILYLATION OF ACETOPHENONE BY RHODIUM CHIRAL ALKYL PHENANTHROLINE CATALYSTS. TETRAHEDRON-ASYMMETRY, 1 (12). pp. 937-942. ISSN 0957-4166,
Full text not available from this repository.Abstract
The in situ catalysts prepared from [Rh(Cod)Cl]2 (Cod = 1,5-cyclooctadiene) and chiral alkylphenanthroline ligands 1-6 display a remarkable activity in the asymmetric hydrosilylation of acetophenone affording, after hydrolysis, the expected 1-phenylethanol in high yield and complete selectivity. High enantioselectivities, up to 76%, were obtained in the presence of 2-substituted derivatives 5 and 6, whereas 3-alkylphenanthrolines 1-4 gave e.e.'s not higher than 6%. High chemical yields, but modest enantioselectivities (10-20% e.e.) were recorded with the potentially terdentate ligands 7-10. Chiral alkylphenanthrolines were poorly efficient ligands in the asymmetric Ni-catalysed cross-coupling of -alpha-methylbenzylmagnesium chloride with vinyl bromide.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSFER HYDROGENATION; NITROGEN LIGANDS; COMPLEXES; KETONES; |
| Depositing User: | Dr. Gernot Deinzer |
| Last Modified: | 19 Oct 2022 08:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/55622 |
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