Low incidence of SARS-CoV-2 infections in healthcare workers at a tertiary care hospital Results of a prospective serological cohort study of the first and second COVID-19 pandemic wave

Hupf, Julian and Burkhardt, Ralph and Gessner, Andre and Maier-Stocker, Constantin and Zimmermann, Markus and Hanses, Frank and Peterhoff, David (2022) Low incidence of SARS-CoV-2 infections in healthcare workers at a tertiary care hospital Results of a prospective serological cohort study of the first and second COVID-19 pandemic wave. MEDIZINISCHE KLINIK-INTENSIVMEDIZIN UND NOTFALLMEDIZIN, 117 (8). pp. 639-643. ISSN 2193-6218, 2193-6226

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Abstract

Background Healthcare workers caring for coronavirus disease 2019 (COVID-19) patients are at an increased risk for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of this seroepidemiological study was to evaluate the risk of infection for employees at a tertiary care hospital. Methods Serological tests for antibodies against SARS-CoV-2 were carried out in a prospective cohort of employees directly involved in the care of COVID-19 patients every 2 weeks from March to July 2020 (1st wave). Antibody status was examined again between December 2020 and February 2021 (2nd wave). Results The seroprevalence of antibodies against SARS-CoV-2 was 5.1% at the end of the study in February 2021. The cumulative incidence was 3.9% after a median observation period of 261 days. Conclusion We observed a low risk of SARS-CoV-2 infection comparable to that of the general population in the examined cohort of healthcare workers involved in the acute care of COVID-19 patients under the applied hygiene and protective measures.

Item Type: Article
Uncontrolled Keywords: ; COVID-19; Hospital personnel; Seroprevalence; Antibody status; SARS-CoV-2
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Medicine > Abteilung für Krankenhaushygiene und Infektiologie
Medicine > Notfallambulanz
Depositing User: Dr. Gernot Deinzer
Date Deposited: 17 Oct 2023 05:35
Last Modified: 17 Oct 2023 05:35
URI: https://pred.uni-regensburg.de/id/eprint/56461

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