Bogovic, Niklas and Doenecke, Axel and Hart, Christina and Luerken, Lukas and Heimerl, Susanne and Eissnert, Christoph and Schlitt, Hans J. and Bitterer, Florian (2022) Covid19 vaccination-associated portal vein thrombosis-An interdisciplinary clinical challenge. CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 46 (8): 101932. ISSN 2210-7401, 2210-741X
Full text not available from this repository. (Request a copy)Abstract
Despite one of the largest vaccination campaigns in human history, the COVID-19 pandemic has not been yet defeated. More than 10 billion doses of COVID-19 vaccine have been administered worldwide. AstraZeneca's Vaxzevria (ChAdOx1 nCoV-19 / AZD1222) was approved as the first viral vector-based vaccine in the EU on 29 January 2021. Thromboembolic events are a rare complication of vaccination with ChAdOx1 nCoV-19 in the context of, now known as vaccine-induced immune thrombotic thrombocytopenia (VITT), with an incidence of 1.5-3 in 100,000 vaccinations. VITT is clinically as well as pathophysiologically comparable to heparininduced thrombocytopenia. Illustrated by a fulminant patient case, a multidisciplinary step-bystep guideline was developed for the recognition, diagnosis, and management of patients with severe acute portosplanchic venous thrombosis with mesenteric ischemia due to vaccineinduced immunogenic thrombotic thrombocytopenia. (C) 2022 Elsevier Masson SAS. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | THROMBOCYTOPENIA; THROMBOLYSIS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Oct 2023 14:29 |
| Last Modified: | 17 Oct 2023 14:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/56471 |
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