Ott, Christian and Proescholdt, Martin and Friedrich, Monika and Hoehne, Julius and Rosengarth, Katharina and Schmidt, Nils-Ole and Schebesch, Karl-Michael (2023) The use of the sodium fluorescein and YELLOW 560 nm filter for the resection of pediatric posterior fossa lesions. CHILDS NERVOUS SYSTEM, 39 (6). pp. 1495-1500. ISSN 0256-7040, 1433-0350
Full text not available from this repository. (Request a copy)Abstract
Purpose This study aimed to verify the feasibility, safety, and benefit of using fluorescein sodium (FL) and a YELLOW 560 nm filter in posterior fossa tumors in children. Methods All cases of pediatric posterior fossa tumors that have undergone surgery using fluorescein (2018-2022) have been included and were examined retrospectively. In those cases where resection of the tumor was planned, a blinded neuroradiologist distinguished gross total resection and subtotal resection according to the postoperative MRI findings. The surgical report and medical files were reviewed regarding the intraoperative staining grade and adverse events. The grade of fluorescent staining of the targeted lesion was assessed as described in the surgical reports. The screening was conducted for any reference to the degree of fluorescent staining: "intense, " "medium, " "slight, " and "no staining. " Results 19 cases have been included. In 14 cases, a complete resection was initially intended. In 11 of these cases, a gross total resection could be achieved (78.6%). Staining was described as intense in most cases (58.8%). Except for yellow-colored urine, no side effects obviously related to FL were found throughout the observation period. Conclusion In combination with a specific filter, FL is a reliable, safe, and feasible tool in posterior fossa surgery in children.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HIGH-GRADE GLIOMAS; GUIDED RESECTION; BRAIN; SURGERY; BLOOD; Neurosurgery; Posterior Fossa; Child; Fluorescein |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurochirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Mar 2024 07:49 |
| Last Modified: | 05 Mar 2024 07:49 |
| URI: | https://pred.uni-regensburg.de/id/eprint/56543 |
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