Kilic, Mustafa and Wendl, Christina and Wilfling, Sibylle and Olmes, David and Linker, Ralf Andreas and Schlachetzki, Felix (2022) Acute Middle Cerebral Artery Occlusion Detection Using Mobile Non-Imaging Brain Perfusion Ultrasound-First Case. JOURNAL OF CLINICAL MEDICINE, 11 (12): 3384. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Mobile brain perfusion ultrasound (BPU) is a novel non-imaging technique creating only hemispheric perfusion curves following ultrasound contrast injection and has been specifically designed for early prehospital large vessel occlusion (LVO) stroke identification. We report on the first patient investigated with the SONAS (R) system, a portable point-of-care ultrasound system for BPU. This patient was admitted into our stroke unit about 12 h following onset of a fluctuating motor aphasia, dysarthria and facial weakness resulting in an NIHSS of 3 to 8. Occlusion of the left middle cerebral artery occlusion was diagnosed by computed tomography angiography. BPU was performed in conjunction with injection of echo-contrast agent to generate hemispheric perfusion curves and in parallel, conventional color-coded sonography (TCCS) assessing MCAO. Both assessments confirmed the results of angiography. Emergency mechanical thrombectomy (MT) achieved complete recanalization (TICI 3) and post-interventional NIHSS of 2 the next day. Telephone follow-up after 2 years found the patient fully active in professional life. Point-of-care BPU is a non-invasive technique especially suitable for prehospital stroke diagnosis for LVO. BPU in conjunction with prehospital stroke scales may enable goal-directed stroke patient placement, i.e., directly to comprehensive stroke centers aiming for MT. Further results of the ongoing phase II study are needed to confirm this finding.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ACUTE STROKE; ENDOVASCULAR THROMBECTOMY; TRANSCRANIAL ULTRASOUND; ACCESS; prehospital stroke diagnosis; large vessel occlusion; ultrasound; thrombectomy; brain perfusion; SONAS (R); prehospital stroke scales; point-of-care diagnostics |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurologie Medicine > Zentrum für Neuroradiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Feb 2024 06:17 |
| Last Modified: | 13 Feb 2024 06:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/56559 |
Actions (login required)
 |
View Item |
