Bärtl, Christoph and Henze, Gina-Isabelle and Giglberger, Marina and Peter, Hannah L. and Konzok, Julian and Wallner, Stefan and Kreuzpointner, Ludwig and Wuest, Stefan and Kudielka, Brigitte M. (2022) Higher allostatic load in work-related burnout: The Regensburg Burnout Project. PSYCHONEUROENDOCRINOLOGY, 143: 105853. ISSN 0306-4530, 1873-3360
Full text not available from this repository. (Request a copy)Abstract
Background: Burnout and chronic work stress have been linked to various negative health outcomes. While the mechanisms underlying this interplay are still unclear, the allostatic load (AL) model was suggested to demonstrate a possible biological pathway. However, previous studies provided divergent results regarding the association between burnout and AL, probably also due to the heterogeneity of selected samples. Therefore, the aim of the present study was to examine differences in AL between a conceptually strictly specified group of individuals suffering from burnout (BO group) and a healthy comparison group (HC group).Methods: After a multi-stage recruitment procedure with strict inclusion criteria based on burnout symptomatology and pathogenesis, the BO group (n = 56) was compared to the HC group (n = 65) regarding an index of AL. The AL-index included 14 parameters: high-sensitivity c-reactive protein (hsCRP), tumor necrosis factoralpha (TNF-alpha), interleukin 6 (IL-6), fibrinogen, d-dimer, plasminogen activator inhibitor 1 (PAI-1), glycosylated hemoglobin (HbA1c), high-density lipoprotein (HDL) cholesterol, total cholesterol to HDL cholesterol ratio (TC/HDL), dehydroepiandrosterone-sulphate (DHEA-S), systolic blood pressure (SBP), diastolic blood pressure (DBP), waist-hip ratio (WHR), and body fat percentage.Results: The BO group showed significantly higher AL-scores in comparison to the HC group. This effect remained significant after adjusting for sex, age, and smoking status. Additionally, burnout symptoms (assessed with the Maslach Burnout Inventory; MBI), MBI-subscales emotional exhaustion and depersonalization as well as chronic work stress (assessed with the effort-reward imbalance questionnaire) were significantly associated with higher AL-scores.Conclusions: Consistent with our hypothesis, we detected higher AL-scores in the BO compared to the HC group, indicating a greater cumulative physiological burden in individuals suffering from burnout. Given the high heterogeneity in individuals experiencing burnout symptoms, future studies may focus on well-specified subgroups, when examining the association between burnout and psychophysiological dysregulations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EFFORT-REWARD IMBALANCE; STRESS-RELATED EXHAUSTION; RISK; DISEASE; HEALTH; DEPRESSION; MACARTHUR; DISORDER; Allostatic load; Burnout; Chronic work stress; Effort -reward imbalance; Regensburg Burnout Project; Depression |
| Subjects: | 100 Philosophy & psychology > 150 Psychology 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin Medicine > Institut für Epidemiologie und Präventivmedizin Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie VII (Medizinische Psychologie, Psychologische Diagnostik und Methodenlehre) - Prof. Dr. Brigitte Kudielka |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Jan 2024 06:03 |
| Last Modified: | 26 Jan 2024 06:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/56621 |
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