Ferreira-Cerca, Sebastien (2022) The dark side of the ribosome life cycle. RNA BIOLOGY, 19 (1). pp. 1045-1049. ISSN 1547-6286, 1555-8584
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Thanks to genetics, biochemistry, and structural biology many features of the ribosome ' s life cycles in models of bacteria, eukaryotes, and some organelles have been revealed to near-atomic details. Collectively, these studies have provided a very detailed understanding of what are now well-established prototypes for ribosome biogenesis and function as viewed from a 'classical' model organisms perspective. However, very important challenges remain ahead to explore the functional and structural diversity of both ribosome biogenesis and function across the biological diversity on earth. Particularly, the 'third domain of life', the archaea, and also many non-model bacterial and eukaryotic organisms have been comparatively neglected. Importantly, characterizing these additional biological systems will not only offer a yet untapped window to enlighten the evolution of ribosome biogenesis and function but will also help to unravel fundamental principles of molecular adaptation of these central cellular processes.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ARCHAEBACTERIUM SULFOLOBUS; HALOARCULA-MARISMORTUI; TOTAL RECONSTITUTION; STRUCTURAL BASIS; MODEL ORGANISMS; RNA; ARCHAEA; SUBUNITS; 16S; BACTERIA; Ribosome; ribosome biogenesis; archaea; non-model organism; RNA |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Nov 2023 08:11 |
| Last Modified: | 14 Nov 2023 08:11 |
| URI: | https://pred.uni-regensburg.de/id/eprint/56644 |
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