Gender Differences in Quality of Life of Metastatic Lung Cancer Patients

Koch, Myriam and Rasch, Frederike and Rothammer, Tobias and Mueller, Karolina and Mohr, Arno and Koller, Michael and Schulz, Christian (2022) Gender Differences in Quality of Life of Metastatic Lung Cancer Patients. CANCER MANAGEMENT AND RESEARCH, 14. pp. 2971-2977. ISSN 1179-1322,

Full text not available from this repository. (Request a copy)

Abstract

Background: Gender aspects in lung cancer patients are a topic of growing interest. But little is known about gender aspects affecting the quality of life (QoL) for those with this life-threatening disease. The aim of the following study was to investigate how gender differences affect QoL in metastatic lung cancer patients.Methods: In a prospective, multicenter study patients filled out the EORTC QLQ-C30 questionnaire and the recently updated lung cancer module QLQ-LC29 at an undefined point in time during first-line therapy. Gender differences were calculated for all QoL scores using ANCOVAs, which controlled for confounders.Results: A total of 130 patients with metastatic lung cancer (UICC stage IV) (46 female and 84 male, mean age 66 years) were enrolled in this study by completing the questionnaires. The only significant gender difference in QoL was found regarding hair loss (mean women= 42.498, mean men=25.490, p-value= 0.010), although women received fewer chemotherapy treatments than men (women n=34, 74% and men n=68, 84%).Conclusion: This study provides evidence that the typical cancer related gender difference effect on QoL, suggesting that men suffer less than women, cannot be found in metastatic tumor stages of lung cancer patients.

Item Type: Article
Uncontrolled Keywords: QUESTIONNAIRE EORTC QLQ-C30; REFERENCE VALUES; SYMPTOM BURDEN; FATIGUE; MANAGEMENT; SURVIVAL; PAIN; SEX; AGE; metastatic lung cancer; gender differences; quality of life; EORTC QLQ-C30; QLQ-LC29
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin II
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien
Depositing User: Dr. Gernot Deinzer
Date Deposited: 27 Nov 2023 08:08
Last Modified: 27 Nov 2023 08:08
URI: https://pred.uni-regensburg.de/id/eprint/56810

Actions (login required)

View Item View Item