Hatzipanagiotou, Maria Eleni and Huber, Deborah and Gerthofer, Valeria and Hetterich, Madeleine and Ripoll, Blanca Roca and Ortmann, Olaf and Seitz, Stephan (2022) Feasibility of ABUS as an Alternative to Handheld Ultrasound for Response Control in Neoadjuvant Breast Cancer Treatment. CLINICAL BREAST CANCER, 22 (2). E142-E146. ISSN 1526-8209, 1938-0666
Full text not available from this repository. (Request a copy)Abstract
This study evaluated the use of Automated Breast Ultrasound Screening (ABUS) for response control in neoadjuvant chemotherapy. Response controls via ABUS and handheld ultrasound were compared with pathologic tumor size. There was no statistical difference between the measurements with handheld ultrasound or ABUS. ABUS seems to be a suitable method to conduct response control in neoadjuvant breast cancer treatment. Introduction: The Invenia Automated Breast Ultrasound Screening (ABUS) is indicated as an adjunct to mammography for breast cancer screening in asymptomatic women with high-density breast tissue. ABUS provides time-efficient evaluation of the 3-dimensional recordings within 3 to 6 minutes. The role and advantages of ABUS in everyday clinical practice, especially in routine examination during neoadjuvant chemotherapy (NACT), is not clear. The aim of this monocentric, noninterventional retrospective study is to evaluate the use of ABUS in patients who are under NACT treatment for response control. Methods: Regular sonographic response check with handheld ultrasound (HHUS) examination and with ABUS were conducted in 83 women who underwent NACT. The response controls were conducted every 3 to 6 weeks during NACT. The handheld sonography was performed with GE Voluson S8. Handheld sonographic measurements and ABUS measurements were compared with the final pathologic tumor size. Results: There was no statistical difference between the measurements with HHUS examination or ABUS compared with final pathologic tumor size (P =.47). The average difference from ABUS measured tumor size to final pathologic tumor size was 9.8 mm. The average difference from handheld measured tumor size to final pathologic tumor size was 9/3 mm. Both the specificity of ABUS and HHUS examination in predicting pathologic complete remission was 100%. Conclusion: ABUS seems to be a suitable method to conduct response control in neoadjuvant breast cancer treatment. ABUS may facilitate preoperative planning and offers remarkable time saving for physicians compared with HHUS examination and thus should be considered for clinical practice (C) 2021 Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CLINICAL EXAMINATION; TUMOR RESPONSE; MAMMOGRAPHY; ACCURACY; CHEMOTHERAPY; MRI; ULTRASONOGRAPHY; SONOGRAPHY; Automatic breast ultrasound; Neoadjuvant chemotherapy; Response control; Breast cancer; Imaging modalities |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Dec 2023 10:17 |
| Last Modified: | 12 Dec 2023 10:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/57006 |
Actions (login required)
 |
View Item |
